"ERCC6" Related Products


Recombinant Human ERCC6

Cat.No.: ERCC6-26417TH
Product Overview: Recombinant fragment of Human CSB with a N terminal proprietary tag: predicted molecular weight 36.63 kDa inclusive of tag.
Description: This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B.
Protein length: 100 amino acids
Molecular Weight: 36.630kDa inclusive of tags
Source: Wheat germ
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the SNF2/RAD54 helicase family.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain.
Gene Name: ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6 [ Homo sapiens ]
Official Symbol: ERCC6
Synonyms: ERCC6; excision repair cross-complementing rodent repair deficiency, complementation group 6; CKN2; DNA excision repair protein ERCC-6; Cockayne syndrome B protein; CSB; RAD26;
Gene ID: 2074
mRNA Refseq: NM_000124
Protein Refseq: NP_000115
MIM: 609413
Uniprot ID: Q03468
Chromosome Location: 10q11
Pathway: DNA Repair, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Formation of transcription-coupled NER (TC-NER) repair complex, organism-specific biosystem; Nucleotide Excision Repair, organism-specific biosystem; Nucleotide excision repair, organism-specific biosystem;
Function: ATP binding; DNA binding; NOT DNA helicase activity; DNA-dependent ATPase activity; chromatin binding;

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