||Monocyte chemotactic protein-1 (MCP-1) is an essential chemokine produced predominantly by macrophages and endothelial cells and is a potent chemotactic factor for monocytes. It can induce the proliferation and activation of killer cells known as CHAK (CC-Chemokine-activated killer). MCP-1 is also a potent activator of human basophils, induces degranulation and the release of histamines. MCP-1 is involved in the pathogenesis of atherosclerosis and myocardial infarction.
|State Of Matter:
||>97% by SDS Page and analyzed by silver stain.
||<0.1 ng per 1 µg as determined by the LAL method.
||The predicted molecular weight of Recombinant Human MCP-1 is Mr 35 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-95 kDa.
|Storage And Stability:
||This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.