"CCL5" Related Products

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Recombinant Human Chemokine (C-C Motif) Ligand 5

Cat. No. : CCL5-125H
Description : RANTES also known as Chemokine (C-C motif) ligand 5 (CCL5), a CC-chemokine is an important mediators of the immune and inflammatory response. It is also a potent chemoattractant for T cells and eosinophils. RANTES is involved in many inflammatory diseases, for example, bronchial asthma, delayed-type hypersensitivity reactions, viral infections, arthritis, chronic eosinophilic pneumonia, and idiopathic interstitial pneumonia.
Source : NSO Cells.
State Of Matter : Lyophilized.
Purity : >90% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Molecular Weight : The predicted molecular weight of Recombinant Human RANTES is Mr 34 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 85-105 kDa.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
PDB rendering based on 1pmi. :

Gene Name : CCL5 chemokine (C-C motif) ligand 5 [ Homo sapiens ]
Synonyms : CCL5; chemokine (C-C motif) ligand 5; SISd; beta-chemokine RANTES; EoCP; RANTES; TCP228; MGC17164; SCYA5; RANTES; TCP228; D17S136E; MGC17164; chemokine (C-C motif) ligand 5; regulated upon activation; normally T-expressed; and presumably secrete; presumably secreted; small inducible cytokine A5; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys); member 5; Small-inducible cytokine A5; Small-inducible cytokine A5; T cell-specific protein P228; Eosinophil-chemotactic cytokine; RANTES(3-68); RANTES(4-68); T-cell specific RANTES protein; T-cell-specific protein RANTES; SIS-delta
Gene ID : 6352
mRNA Refseq : NM_002985
Protein Refseq : NP_002976
MIM : 187011
UniProt ID : P13501
Chromosome Location : 17q11.2-q12
Pathway : Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Prion diseases; Toll-like receptor signaling pathway; Signaling by GPCR
Function : chemoattractant activity; chemokine activity; signal transducer activity

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