Species : |
Human |
Tag : |
His |
Protein Length : |
29-760 a.a. |
Description : |
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. |
Conjugation : |
HIS |
Tissue specificity : |
Fibroblast specific. |
Biological activity : |
Specific Activity: 10.2 pmol/min/μg.Assay Condition: 50 mM Tris-HCl (pH7.5), 10 mM MgCl2, 1 mM MnCl2, 5μM substrate (A-P-AMC), room temperature. |
Form : |
Liquid |
Purity : |
>90% by SDS-PAGE |
Storage buffer : |
Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0 |
Storage : |
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : |
Belongs to the peptidase S9B family. |