"FGF19" Related Products

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Recombinant Human FGF19 Protein, Fc-tagged

Cat.No. : FGF19-28824TH
Product Overview : Recombinant Human FGF19(aa 1-216) fused with the C-terminus the Fc portion of human IgG1 was expressed in HEK 293 cells.
Description : FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Source : HEK 293 cells
Species : Human
Tag : Fc
Form : Lyophilized from 0.2μm-filtered solution in PBS, pH 7.2.
Molecular Mass : ~50kDa (SDS-PAGE)
Protein length : aa 1-216
Endotoxin : <0.1EU/μg purified protein (LAL test; Lonza).
Purity : ≥90% (SDS-PAGE)
Stability : Stable for at least 6 months after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade.
Storage : Short Term Storage +4 centigrade;
Long Term Storage -20 centigrade;
After reconstitution, prepare aliquots and store at -20 centigrade. Avoid freeze/thaw cycles.
Reconstitution : Reconstitute in distilled water.
Gene Name : FGF19 fibroblast growth factor 19 [ Homo sapiens ]
Official Symbol : FGF19
Synonyms : FGF19; fibroblast growth factor 19; FGF-19;
Gene ID : 9965
mRNA Refseq : NM_005117
Protein Refseq : NP_005108
MIM : 603891
UniProt ID : O95750

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