Recombinant Human FKBP2 FKBP2-28913TH

Recombinant Human FKBP2

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Recombinant Human FKBP2

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Cat.No. : FKBP2-28913TH
Product Overview : Recombinant Human full-length mature FKBP2, amino acids 22-142, predicted MWt 13.4 kDa.
Description : The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Protein length : 121 amino acids
Molecular Weight : 13.400kDa
Source : E. coli
Tissue specificity : T-cells and thymus.
Biological activity : Specific activity is >150 nmoles/min/ug, and is defined as the amount of enzyme that cleave 1umole of suc-AAFP-pNA per minute at 1C in Tris-Hcl pH8.0 using chymotrypsin.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:10% Glycerol, 0.32% Tris HCl, 0.02% DTT
Storage : Please see Notes section
Sequences of amino acids : MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL.
Sequence Similarities : Belongs to the FKBP-type PPIase family. FKBP2 subfamily.Contains 1 PPIase FKBP-type domain.
Gene Name : FKBP2 FK506 binding protein 2, 13kDa [ Homo sapiens ]
Official Symbol : FKBP2
Synonyms : FKBP2; FK506 binding protein 2, 13kDa; FK506 binding protein 2 (13kD); peptidyl-prolyl cis-trans isomerase FKBP2; FKBP 13; peptidyl prolyl cis trans isomerase; PPIase; proline isomerase; rapamycin binding protein;
Gene ID : 2286
mRNA Refseq : NM_001135208
Protein Refseq : NP_001128680
MIM : 186946
Uniprot ID : P26885
Chromosome Location : 11q13.1-q13.3
Function : FK506 binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding;

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