Recombinant Human FKBP2
Cat.No. : | FKBP2-28913TH |
Product Overview : | Recombinant Human full-length mature FKBP2, amino acids 22-142, predicted MWt 13.4 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Protein length : | 121 amino acids |
Molecular Weight : | 13.400kDa |
Source : | E. coli |
Tissue specificity : | T-cells and thymus. |
Biological activity : | Specific activity is >150 nmoles/min/ug, and is defined as the amount of enzyme that cleave 1umole of suc-AAFP-pNA per minute at 1C in Tris-Hcl pH8.0 using chymotrypsin. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:10% Glycerol, 0.32% Tris HCl, 0.02% DTT |
Storage : | Please see Notes section |
Sequences of amino acids : | MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL. |
Sequence Similarities : | Belongs to the FKBP-type PPIase family. FKBP2 subfamily.Contains 1 PPIase FKBP-type domain. |
Gene Name : | FKBP2 FK506 binding protein 2, 13kDa [ Homo sapiens ] |
Official Symbol : | FKBP2 |
Synonyms : | FKBP2; FK506 binding protein 2, 13kDa; FK506 binding protein 2 (13kD); peptidyl-prolyl cis-trans isomerase FKBP2; FKBP 13; peptidyl prolyl cis trans isomerase; PPIase; proline isomerase; rapamycin binding protein; |
Gene ID : | 2286 |
mRNA Refseq : | NM_001135208 |
Protein Refseq : | NP_001128680 |
MIM : | 186946 |
Uniprot ID : | P26885 |
Chromosome Location : | 11q13.1-q13.3 |
Function : | FK506 binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
FKBP2-4188H | Recombinant Human FKBP2 Protein, GST-tagged | +Inquiry |
Fkbp2-3025M | Recombinant Mouse Fkbp2 Protein, Myc/DDK-tagged | +Inquiry |
FKBP2-343H | Recombinant Human FKBP2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
FKBP2-734H | Recombinant Human FKBP2 Protein, His-tagged | +Inquiry |
FKBP2-3268M | Recombinant Mouse FKBP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FKBP2-6207HCL | Recombinant Human FKBP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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