Recombinant Human FLT4
Cat.No. : | FLT4-31719TH |
Product Overview : | Recombinant fragment, produced in a Baculovirus expression system, corresponding to amino acids 798-1298 of Human VEGF Receptor 3, with a N terminal proprietary tag, 82 kDa,. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. |
Source : | Baculovirus |
Tissue specificity : | Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. |
Biological activity : | Specific Activity: 17 pmol/min/μg.Assay conditions: VEGFR3 was incubated with a substrate (Tyr peptide 4 for 1h at RT in 1Xkinase buffer supplemented with ATP. Developer solution was added to reaction and reaction was stopped after 1h of incubation at RT. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 138mM Sodium chloride, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.Contains 7 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 protein kinase domain. |
Gene Name : | FLT4 fms-related tyrosine kinase 4 [ Homo sapiens ] |
Official Symbol : | FLT4 |
Synonyms : | FLT4; fms-related tyrosine kinase 4; vascular endothelial growth factor receptor 3; PCL; VEGFR3; |
Gene ID : | 2324 |
mRNA Refseq : | NM_002020 |
Protein Refseq : | NP_002011 |
MIM : | 136352 |
Uniprot ID : | P35916 |
Chromosome Location : | 5q34-q35 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Signal Transduction, organism-specific biosystem; |
Function : | ATP binding; growth factor binding; nucleotide binding; protein binding; protein phosphatase binding; |
Products Types
◆ Recombinant Protein | ||
FLT4-4377H | Active Recombinant Human FLT4 Protein, GST/His-tagged | +Inquiry |
FLT4-101H | Recombinant Human FLT4 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
FLT4-4379H | Recombinant Human FLT4 Protein, GST-tagged | +Inquiry |
FLT4-478H | Recombinant Human FLT4 Protein, Fc-tagged | +Inquiry |
FLT4-2055H | Recombinant Human FLT4 Protein, Fc/His-tagged | +Inquiry |
◆ Lysates | ||
FLT4-2709HCL | Recombinant Human FLT4 cell lysate | +Inquiry |
FLT4-2016MCL | Recombinant Mouse FLT4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1594 | Flt4 Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket