||Recombinant full length protein (Human). Expressed in insect cells infected with recombinant baculovirus (Autographa californica) containing cDNA inserts for human FMO1.
||Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region.Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
||Expressed mainly in fetal liver, adult kidney and, to a lesser extent, the intestine.
||Preservative: NoneConstituents: 100mM Potassium phosphate buffer, pH 7.4
||Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
||Belongs to the FMO family.