Recombinant Human FOS, GST-tagged
Cat.No. : | FOS-26602TH |
Product Overview : | Recombinant full-length human FOS was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~78 kDa |
Purity : | >90% |
Applications : | Kinase Assay; Western Blot |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.2 ug/ul |
Gene Name : | FOS FBJ murine osteosarcoma viral oncogene homolog [ Homo sapiens ] |
Official Symbol : | FOS |
Synonyms : | FOS; p55; AP-1; C-FOS; FBJ murine osteosarcoma viral oncogene homolog; proto-oncogene c-Fos; activator protein 1; cellular oncogene c-fos; G0/G1 switch regulatory protein 7; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS) |
Gene ID : | 2353 |
mRNA Refseq : | NM_005252 |
Protein Refseq : | NP_005243 |
MIM : | 164810 |
UniProt ID : | P01100 |
Chromosome Location : | 14q24.3 |
Pathway : | ATF-2 transcription factor network; Activated TLR4 signalling; Activation of the AP-1 family of transcription factors |
Function : | R-SMAD binding; double-stranded DNA binding; sequence-specific DNA binding |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionElevated levels of FOS protein in specific diseases may serve as a prognostic marker, indicating disease severity and progression.
FOS protein plays a crucial role in signaling pathways, providing insights into how cells respond to various stimuli, including stress and growth factors.
FOS protein acts as a transcription factor, regulating the expression of genes involved in cell proliferation, differentiation, and survival.
FOS protein analysis can provide valuable information for tailoring treatment strategies based on the individual's molecular profile, contributing to personalized medicine.
Targeting FOS protein for therapeutic purposes can be challenging due to its involvement in various cellular processes, requiring precise modulation.
Customer Reviews (3)
Write a reviewIts reliability and high quality make it a valuable tool in various applications, ranging from enzymatic assays to studying protein-protein interactions.
The FOS protein is highly regarded for its excellent performance in WB assays and its significant contribution to protein EM structure analysis.
The FOS protein is highly recommended for researchers conducting protein studies, especially in Western blotting (WB) experiments.
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