Recombinant Human FOS, His-tagged


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Recombinant Human FOS, His-tagged

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Cat.No. : FOS-27240TH
Product Overview : Recombinant full length Human c-Fos with His tag expressed in a baculovirus system, 41kDa.
Description : The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2.These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Conjugation : HIS
Biological activity : 1 unit equals 1 nanogram of purified protein.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the bZIP family. Fos subfamily.Contains 1 bZIP domain.
Gene Name : FOS FBJ murine osteosarcoma viral oncogene homolog [ Homo sapiens ]
Official Symbol : FOS
Synonyms : FOS; FBJ murine osteosarcoma viral oncogene homolog; v fos FBJ murine osteosarcoma viral oncogene homolog; proto-oncogene c-Fos; AP 1; c fos;
Gene ID : 2353
mRNA Refseq : NM_005252
Protein Refseq : NP_005243
MIM : 164810
Uniprot ID : P01100
Chromosome Location : 14q24.3
Pathway : ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of the AP-1 family of transcription factors, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem;
Function : R-SMAD binding; double-stranded DNA binding; protein binding; protein dimerization activity; sequence-specific DNA binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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