"FOS" Related Products

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Recombinant Human FOS, His-tagged

Cat.No.: FOS-27240TH
Product Overview: Recombinant full length Human c-Fos with His tag expressed in a baculovirus system, 41kDa.
Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2.These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Conjugation: HIS
Biological activity: 1 unit equals 1 nanogram of purified protein.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the bZIP family. Fos subfamily.Contains 1 bZIP domain.
Gene Name: FOS FBJ murine osteosarcoma viral oncogene homolog [ Homo sapiens ]
Official Symbol: FOS
Synonyms: FOS; FBJ murine osteosarcoma viral oncogene homolog; v fos FBJ murine osteosarcoma viral oncogene homolog; proto-oncogene c-Fos; AP 1; c fos;
Gene ID: 2353
mRNA Refseq: NM_005252
Protein Refseq: NP_005243
MIM: 164810
Uniprot ID: P01100
Chromosome Location: 14q24.3
Pathway: ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of the AP-1 family of transcription factors, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem;
Function: R-SMAD binding; double-stranded DNA binding; protein binding; protein dimerization activity; sequence-specific DNA binding;

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