Recombinant Human FOS, His-tagged

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Recombinant Human FOS, His-tagged

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Cat.No. : FOS-27240TH
Product Overview : Recombinant full length Human c-Fos with His tag expressed in a baculovirus system, 41kDa.
Description : The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2.These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Conjugation : HIS
Biological activity : 1 unit equals 1 nanogram of purified protein.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the bZIP family. Fos subfamily.Contains 1 bZIP domain.
Gene Name : FOS FBJ murine osteosarcoma viral oncogene homolog [ Homo sapiens ]
Official Symbol : FOS
Synonyms : FOS; FBJ murine osteosarcoma viral oncogene homolog; v fos FBJ murine osteosarcoma viral oncogene homolog; proto-oncogene c-Fos; AP 1; c fos;
Gene ID : 2353
mRNA Refseq : NM_005252
Protein Refseq : NP_005243
MIM : 164810
Uniprot ID : P01100
Chromosome Location : 14q24.3
Pathway : ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of the AP-1 family of transcription factors, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem;
Function : R-SMAD binding; double-stranded DNA binding; protein binding; protein dimerization activity; sequence-specific DNA binding;

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