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Recombinant Human GABARAP, His-tagged

Cat.No. : GABARAP-26082TH
Product Overview : Recombinant full length Human GABARAP fused to a His tag at the N terminus; amino acids 1-117 ; predicted mwt: 16 kDa;
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  • Gene Information
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Description : Gamma-aminobutyric acid A receptors
Conjugation : HIS
Source : E. coli
Tissue specificity : Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MKFVYKEEHP FEKRRSEGEK IRKKYPDRVPVIVEKAPKAR IGDLDKKKYL VPSDLTVGQF YFLIRKRIHL RAEDALFFFVNNVIPPTSAT MGQLYQEHHE EDFFLYIAYS DESVYGL
Sequence Similarities : Belongs to the MAP1 LC3 family.
Gene Name : GABARAP GABA(A) receptor-associated protein [ Homo sapiens ]
Official Symbol : GABARAP
Synonyms : GABARAP; GABA(A) receptor-associated protein; gamma-aminobutyric acid receptor-associated protein; ATG8A; MM46;
Gene ID : 11337
mRNA Refseq : NM_007278
Protein Refseq : NP_009209
MIM : 605125
Uniprot ID : O95166
Chromosome Location : 17p13.1
Pathway : GABAergic synapse, organism-specific biosystem; GABAergic synapse, conserved biosystem; Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; Senescence and Autophagy, organism-specific biosystem;
Function : GABA receptor binding; beta-tubulin binding; microtubule binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What are the mechanisms by which GABARAP modulates protein aggregation and degradation in cells? 06/09/2022

GABARAP contributes to protein aggregation and degradation processes, crucial in maintaining cellular health.

How does GABARAP influence the trafficking and surface expression of GABA receptors? 01/09/2022

GABARAP impacts GABA receptor trafficking and surface expression, affecting receptor availability and signaling.

What is the impact of GABARAP on immune cell function and inflammatory responses? 07/07/2021

GABARAP plays a role in immune cell functioning and modulates inflammatory responses.

How does GABARAP participate in the process of autophagy and cellular homeostasis? 02/08/2021

GABARAP is involved in autophagy, aiding in the degradation and recycling of cellular components for homeostasis.

How does GABARAP contribute to the pathophysiology of neurological disorders, such as Alzheimer's disease? 04/30/2020

GABARAP is linked to the pathology of neurological disorders, potentially affecting protein aggregation and neuronal function.

What role does GABARAP play in neuronal signaling and the regulation of GABAergic synapses? 05/31/2018

GABARAP regulates neuronal signaling, particularly at GABAergic synapses, influencing neurotransmission.

How do alterations in GABARAP expression or function affect cancer cell growth and survival? 03/19/2018

Changes in GABARAP expression influence cancer cell behavior, impacting growth, survival, and responsiveness to therapy.

Customer Reviews (3)

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Reviews
09/10/2020

    Precise protein quantification, fundamental for our studies' accuracy.

    08/20/2020

      Efficient protein purification, consistent yields, cost-effective service.

      05/15/2020

        Dependable peptide synthesis, accelerates our peptide-based projects.

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