Recombinant Human GADD45G, His-tagged

• Cat.No.: GADD45G-26076TH
• Product Overview: Recombinant full length protein (Human) fused to His-Tag at N-terminal end.

Specification

• Description: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton X-100, 10mM Tris, pH 8.0
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the GADD45 family.

Gene Information

• Gene Name: GADD45G growth arrest and DNA-damage-inducible, gamma [ Homo sapiens ]
• Official Symbol: GADD45G
• Synonyms: GADD45G; growth arrest and DNA-damage-inducible, gamma; growth arrest and DNA damage-inducible protein GADD45 gamma; CR6; DDIT2; gadd related protein; 17 kD; GADD45gamma; growth arrest and DNA damage inducible gamma; GRP17
• Gene ID: 10912
• mRNA Refseq: NM_006705
• Protein Refseq: NP_006696
• MIM: 604949
• Uniprot ID: O95257
• Chromosome Location: 9q22.1-q22.2
• Pathway: Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; IL12-mediated signaling events, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem
• Function: protein binding