Recombinant Human GATA3

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Recombinant Human GATA3

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Cat.No. : GATA3-28477TH
Product Overview : Recombinant fragment corresponding to amino acids 103-200 of Human GATA3 with a proprietary tag; Predicted MWt 36.41 kDa.
Description : This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Protein length : 98 amino acids
Molecular Weight : 36.410kDa
Source : Wheat germ
Tissue specificity : T-cells and endothelial cells.
Biological activity : useful for Antibody Production and Protein Array
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: glutathione is reduced
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : LGSHHTASPW NLSPFSKTSI HHGSPGPLSV YPPASSSSLS GGHASPHLFT FPPTPPKDVS PDPSLSTPGS AGSARQDEKE CLKYQVPLPD SMKLESSH
Sequence Similarities : Contains 2 GATA-type zinc fingers.
Gene Name : GATA3 GATA binding protein 3 [ Homo sapiens ]
Official Symbol : GATA3
Synonyms : GATA3; GATA binding protein 3; trans-acting T-cell-specific transcription factor GATA-3; HDR;
Gene ID : 2625
mRNA Refseq : NM_001002295
Protein Refseq : NP_001002295
MIM : 131320
Uniprot ID : P23771
Chromosome Location : 10p15
Pathway : Adipogenesis, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem;
Function : DNA binding; E-box binding; HMG box domain binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; core promoter proximal region sequence-specif;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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