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Recombinant Human GCA, His-tagged

Cat.No. : GCA-26242TH
Product Overview : Recombinant full length Human Grancalcin with an N terminal His tag; 237 amino acids with tag, Predicted MWt 26.1 kDa.
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Description : This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
Protein length : 217 amino acids
Conjugation : HIS
Molecular Weight : 26.100kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMAYPG YGGGFGNFSIQVPGMQMGQPVPETG PAILLDGYSGPAYSDTYSSAGDSVY TYFSAVAGQDGEVDAEELQRCLTQS GINGTYSPFSLETCRIMIAMLDRDH TGKMGFNAFKELWAALNAWKENFMT VDQDGSGTVEHHELRQAIGLMGYRL SPQTLTTIVKRYSKNGRIFFDDYVA CCVKLRALTDFFRKRDHLQQGSANF IYDDFLQGTMAI
Gene Name : GCA grancalcin, EF-hand calcium binding protein [ Homo sapiens ]
Official Symbol : GCA
Synonyms : GCA; grancalcin, EF-hand calcium binding protein; grancalcin, EF hand calcium binding protein; grancalcin; GCL;
Gene ID : 25801
mRNA Refseq : NM_012198
Protein Refseq : NP_036330
MIM : 607030
Uniprot ID : P28676
Chromosome Location : 2p14-q14.3
Function : calcium ion binding; protein homodimerization activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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08/31/2020

    In ELISA assays, it has consistently exhibited exceptional reliability and accuracy, providing precise and reproducible results.

    06/26/2019

      Their prompt and knowledgeable guidance has been instrumental in effectively addressing my queries and optimizing the utilization of the GCA protein in my studies.

      09/12/2018

        The GCA protein comes highly recommended for its outstanding performance in various experimental applications.

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