Recombinant Human GLO1
Cat.No. : | GLO1-29068TH |
Product Overview : | Recombinant full length Human GLO1; amino acids 1-184 , 20.7kDa. |
- Specification
- Gene Information
- Related Products
Description : | The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione.Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MAEPQPPSGG LTDEAALSCC SDADPSTKDF LLQQTMLRVK DPKKSLDFYT RVLGMTLIQK CDFPIMKFSL YFLAYEDKND IPKEKDEKIA WALSRKATLE LTHNWGTEDD ETQSYHNGNS DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKM ATLM |
Sequence Similarities : | Belongs to the glyoxalase I family. |
Gene Name : | GLO1 glyoxalase I [ Homo sapiens ] |
Official Symbol : | GLO1 |
Synonyms : | GLO1; glyoxalase I; lactoylglutathione lyase; GLOD1; glyoxalase domain containing 1; |
Gene ID : | 2739 |
mRNA Refseq : | NM_006708 |
Protein Refseq : | NP_006699 |
MIM : | 138750 |
Uniprot ID : | Q04760 |
Chromosome Location : | 6p21.3-p21.1 |
Pathway : | Pyruvate metabolism, organism-specific biosystem; Pyruvate metabolism, conserved biosystem; |
Function : | lactoylglutathione lyase activity; lyase activity; metal ion binding; |
Products Types
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GLO1-4966H | Recombinant Human GLO1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
GLO1-5899HCL | Recombinant Human GLO1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGLO1 is implicated in diabetes and metabolic disorders, influencing glycation end products and insulin signaling.
GLO1 modulates cancer cell growth and spread, affecting tumor development and metastasis.
GLO1 works with the glyoxalase system to regulate cellular detoxification and protect against metabolic stress.
GLO1 expression affects cellular oxidative stress, playing a role in aging and age-related cellular damage.
Genetic variations in GLO1 alter its activity, affecting disease risk and response to metabolic stress.
Changes in GLO1 levels impact neurological function and may contribute to the progression of neurodegenerative diseases.
GLO1 detoxifies methylglyoxal and other aldehydes, preventing cellular damage and maintaining metabolic balance.
Customer Reviews (3)
Write a reviewTimely protein expression optimization; improves our research efficiency.
Accurate protein structural analysis; crucial for our studies.
Dependable antibody validation; boosts our immunoprecipitation studies.
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