Cat.No. :	GPX2-29071TH
Product Overview :	Recombinant full length protein, corresponding to amino acids 1-190 of Human Glutathione Peroxidase 2, with an N-terminal His tag. 210 amino acids with a predicted MWt of 22 kDa
Description :	This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
Protein length :	190 amino acids
Conjugation :	HIS
Molecular Weight :	24.100kDa inclusive of tags
Source :	E. coli
Tissue specificity :	Mostly in liver and gastrointestinal tract, not found in heart or kidney.
Form :	Liquid
Purity :	>95% by SDS-PAGE
Storage buffer :	pH: 7.50Constituents:0.32% Tris HCl, 0.88% Sodium chloride, 0.02% DTT, 40% Glycerol
Storage :	Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids :	MGSSHHHHHH SSGLVPRGSH MAFIAKSFYD LSAISLDGEK VDFNTFRGRA VLIENVASLC GTTTRDFTQL NELQCRFPRR LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFT LVQKCEVNGQ NEHPVFAYLK DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV AWNFEKFLIG PEGEPFRRYS RTFPTINIEP DIKRLLKVAI
Sequence Similarities :	Belongs to the glutathione peroxidase family.

Gene Name :	GPX2 glutathione peroxidase 2 (gastrointestinal) [ Homo sapiens ]
Official Symbol :	GPX2
Synonyms :	GPX2; glutathione peroxidase 2 (gastrointestinal); glutathione peroxidase 2; GSHPX GI;
Gene ID :	2877
mRNA Refseq :	NM_002083
Protein Refseq :	NP_002074
MIM :	138319
Uniprot ID :	P18283
Chromosome Location :	14q24.1
Pathway :	Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Folate Metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem;
Function :	electron carrier activity; glutathione peroxidase activity; oxidoreductase activity;

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