Cat.No. : |
GPX2-29071TH |
Product Overview : |
Recombinant full length protein, corresponding to amino acids 1-190 of Human Glutathione Peroxidase 2, with an N-terminal His tag. 210 amino acids with a predicted MWt of 22 kDa |
Description : |
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. |
Protein length : |
190 amino acids |
Conjugation : |
HIS |
Molecular Weight : |
24.100kDa inclusive of tags |
Source : |
E. coli |
Tissue specificity : |
Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
Form : |
Liquid |
Purity : |
>95% by SDS-PAGE |
Storage buffer : |
pH: 7.50Constituents:0.32% Tris HCl, 0.88% Sodium chloride, 0.02% DTT, 40% Glycerol |
Storage : |
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : |
MGSSHHHHHH SSGLVPRGSH MAFIAKSFYD LSAISLDGEK VDFNTFRGRA VLIENVASLC GTTTRDFTQL NELQCRFPRR LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFT LVQKCEVNGQ NEHPVFAYLK DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV AWNFEKFLIG PEGEPFRRYS RTFPTINIEP DIKRLLKVAI |
Sequence Similarities : |
Belongs to the glutathione peroxidase family. |