Cat. No. : | FGFR1-487H |
Description : | Fibroblast growth factor receptor-1 beta (FGFR1- beta) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGF R1β supports progression and chemoresistance in subsets of acute myeloid leukemias (AML). |
Source : | NSO Cells. |
Molecular Weight : | The predicted molecular weight of Recombinant Human FGF R1β (IIIb) is Mr 56 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 90-100 kDa. |
State Of Matter : | Lyophilized. |
Purity : | > 95% by SDS Page and analyzed by silver stain. |
Endotoxin : | < 1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | FGFR1 fibroblast growth factor receptor 1 [ Homo sapiens ] |
Synonyms : | FGFR1; fibroblast growth factor receptor 1; CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; HBGFR; N-SAM; FLJ99988; OTTHUMP00000190881; soluble FGFR1 variant 1; FMS-like tyrosine kinase 2; ydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1 |
Gene ID : | 2260 |
mRNA Refseq : | NM_015850 |
Protein Refseq : | NP_056934 |
UniProt ID : | P11362 |
Chromosome Location : | 8p12 |
MIM : | 607401 |
Pathway : | Adherens junction; MAPK signaling pathway; elanoma; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton; Axon guidance; Signaling by FGFR |
Function : | ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; transferase activity |
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