Cat. No. :	FGFR1-487H
Description :	Fibroblast growth factor receptor-1 beta (FGFR1- beta) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGF R1β supports progression and chemoresistance in subsets of acute myeloid leukemias (AML).
Source :	NSO Cells.
Molecular Weight :	The predicted molecular weight of Recombinant Human FGF R1β (IIIb) is Mr 56 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 90-100 kDa.
State Of Matter :	Lyophilized.
Purity :	> 95% by SDS Page and analyzed by silver stain.
Endotoxin :	< 1.0 EU/µg as determined by the LAL method.
Storage And Stability :	This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Name :	FGFR1 fibroblast growth factor receptor 1 [ Homo sapiens ]
Synonyms :	FGFR1; fibroblast growth factor receptor 1; CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; HBGFR; N-SAM; FLJ99988; OTTHUMP00000190881; soluble FGFR1 variant 1; FMS-like tyrosine kinase 2; ydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1
Gene ID :	2260
mRNA Refseq :	NM_015850
Protein Refseq :	NP_056934
UniProt ID :	P11362
Chromosome Location :	8p12
MIM :	607401
Pathway :	Adherens junction; MAPK signaling pathway; elanoma; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton; Axon guidance; Signaling by FGFR
Function :	ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; transferase activity

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