"FGFR2" Related Products

Recombinant Human Fibroblast Growth Factor Receptor 2

Cat. No.: FGFR2-489H
Description: This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.
Source: NSO Cells.
Molecular Weight: The predicted molecular weight of Recombinant Human FGF R2α (IIIc) is Mr 66 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100-110 kDa.
State Of Matter: Lyophilized.
Purity: > 90% by SDS Page and analyzed by silver stain.
Endotoxin: < 0.1 ng per 1 µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ]
Synonyms: FGFR2; fibroblast growth factor receptor 2; BEK; JWS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FLJ98662; FGF receptor; OTTHUMP00000020624; OTTHUMP00000020626; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14; EC 2.7.10.1; Crouzon syndrome; Pfeiffer syndrome; craniofacial dysostosis 1; Jackson-Weiss syndrome; Keratinocyte growth factor receptor 2; K-SAM; CD332 antigen; BEK fibroblast growth factor receptor; FGF receptor
Gene ID: 2263
mRNA Refseq: NM_000141
Protein Refseq: NP_000132
UniProt ID: P21802
Chromosome Location: 10q25.3-q26
MIM: 176943
Pathway: Endocytosis; MAPK signaling pathway; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton
Function: ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; receptor activity; transferase activity

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