Recombinant Human HTR2B
Cat.No. : | HTR2B-26027TH |
Product Overview : | Recombinant fragment corresponding to amino acids 1-56 of Human 5HT2B Receptor with N terminal proprietary tag; predicted MWt 31.79 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. |
Protein length : | 56 amino acids |
Molecular Weight : | 31.790kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Detected in most peripheral organs. Only low expression levels were found in the brain. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MALSYRVSELQSTIPEHILQSTFVH VISSNWSGLQTESIPEEMKQIVEEQ GNKLHW |
Sequence Similarities : | Belongs to the G-protein coupled receptor 1 family. |
Gene Name : | HTR2B 5-hydroxytryptamine (serotonin) receptor 2B [ Homo sapiens ] |
Official Symbol : | HTR2B |
Synonyms : | HTR2B; 5-hydroxytryptamine (serotonin) receptor 2B; 5-hydroxytryptamine receptor 2B; 5 HT(2B); 5 HT2B; |
Gene ID : | 3357 |
mRNA Refseq : | NM_000867 |
Protein Refseq : | NP_000858 |
MIM : | 601122 |
Uniprot ID : | P41595 |
Chromosome Location : | 2q36.3-q37.1 |
Pathway : | Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; |
Function : | G-protein alpha-subunit binding; G-protein coupled receptor activity; Ras GTPase activator activity; calcium channel activity; drug binding; |
Products Types
◆ Recombinant Protein | ||
HTR2B-5243H | Recombinant Human HTR2B Protein, GST-tagged | +Inquiry |
HTR2B-2618R | Recombinant Rat HTR2B Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2B-4375M | Recombinant Mouse HTR2B Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2B-1091HFL | Recombinant Human HTR2B protein, His&Flag-tagged | +Inquiry |
HTR2B-5494C | Recombinant Chicken HTR2B | +Inquiry |
◆ Lysates | ||
HTR2B-5335HCL | Recombinant Human HTR2B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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