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Recombinant Human ID2

Cat.No.: ID2-28380TH
Product Overview: Recombinant full length Human ID2 protein with a proprietary tag; predicted molecular weight 40.48 kDa, inclusive of tag. AAH30639
Description: The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.
Protein length: 135 amino acids
Molecular Weight: 40.480kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Highly expressed in early fetal tissues, including those of the central nervous system.
Biological activity: useful for Antibody Production and Protein Array
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Contains 1 basic helix-loop-helix (bHLH) domain.
Gene Name: ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [ Homo sapiens ]
Official Symbol: ID2
Synonyms: ID2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-2; bHLHb26; cell growth inhibiting gene 8; GIG8;
Gene ID: 3398
mRNA Refseq: NM_002166
Protein Refseq: NP_002157
MIM: 600386
Uniprot ID: Q02363
Chromosome Location: 2p25
Pathway: HIF-1-alpha transcription factor network, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function: protein binding;

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