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Recombinant Human ID2

Cat.No. : ID2-28380TH
Product Overview : Recombinant full length Human ID2 protein with a proprietary tag; predicted molecular weight 40.48 kDa, inclusive of tag. AAH30639
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.
Protein length : 135 amino acids
Molecular Weight : 40.480kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Highly expressed in early fetal tissues, including those of the central nervous system.
Biological activity : useful for Antibody Production and Protein Array
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Contains 1 basic helix-loop-helix (bHLH) domain.
Gene Name : ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [ Homo sapiens ]
Official Symbol : ID2
Synonyms : ID2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-2; bHLHb26; cell growth inhibiting gene 8; GIG8;
Gene ID : 3398
mRNA Refseq : NM_002166
Protein Refseq : NP_002157
MIM : 600386
Uniprot ID : Q02363
Chromosome Location : 2p25
Pathway : HIF-1-alpha transcription factor network, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function : protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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