Recombinant Human ING5, His-tagged
Cat.No. : | ING5-27620TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 2-240 of Human ING5 with N terminal His tag; 239 amino acids, kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 71 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | ATAMYLEHYLDSIENLPCELQRNFQ LMRELDQRTEDKKAE IDILAAEYISTVKTLSPDQRVERLQ KIQNAYSKCKEYS DDKVQLAMQTYEMVDKHIRRLDADL ARFEADLKDKMEGSDFESSGGRGLK KGRGQKEKRGSRGRGRRTSEEDTPK KKK HKGGSEFTDTILSVHPSDVLDMPVD PNEPTYCLCHQVS YGEMIGCDNPDCPIEWFHFACVDLT TKPKGKWFCPRCVQEKRKKK |
Gene Name : | ING5 inhibitor of growth family, member 5 [ Homo sapiens ] |
Official Symbol : | ING5 |
Synonyms : | ING5; inhibitor of growth family, member 5; inhibitor of growth protein 5; FLJ23842; p28ING5; |
Gene ID : | 84289 |
mRNA Refseq : | NM_032329 |
Protein Refseq : | NP_115705 |
MIM : | 608525 |
Uniprot ID : | Q8WYH8 |
Chromosome Location : | 2q37.3 |
Function : | metal ion binding; methylated histone residue binding; protein binding; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
ING5-4546M | Recombinant Mouse ING5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ING5-2091R | Recombinant Rhesus Macaque ING5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ING5-5124H | Recombinant Human ING5 Protein, GST-tagged | +Inquiry |
ING5-8211M | Recombinant Mouse ING5 Protein | +Inquiry |
ING5-7383H | Recombinant Human ING5 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ING5-5205HCL | Recombinant Human ING5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionYes, ING5 is known to interact with specific histone modifications, including histone H3 trimethylated at Lysine 4 (H3K4me3).
The interaction between ING5 and H3K4me3 is important for targeting specific chromatin regions and regulating gene expression.
ING5 is known to interact with chromatin remodeling complexes, facilitating changes in chromatin structure and gene expression.
Yes, ING5 has been identified as a potential tumor suppressor, and its loss or dysfunction can contribute to tumorigenesis.
ING5 is involved in cell cycle control, and its expression can impact cell proliferation and the cell cycle progression of cells.
ING5 is a chromatin regulator that plays a role in transcriptional regulation and epigenetic
Mutations or alterations in ING5 have been reported in various cancer types, suggesting its potential role in cancer development.
Customer Reviews (3)
Write a reviewThe knowledge gained from the product's usage justified its cost, marking a prudent investment in our research endeavors.
Despite its cost, the product's contributions to our research goals made it an invaluable asset.
The product's adaptability to various buffers contributed to its stable and reliable performance.
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