Recombinant Human LMX1A
Cat.No. : | LMX1A-29601TH |
Product Overview : | Recombinant full length Human LMX1A (aa 1-100) with N-terminal proprietary tag, 37.07 kDa. |
- Specification
- Gene Information
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Description : | Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al. |
Protein length : | 100 amino acids |
Molecular Weight : | 37.070kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Isoform 1 is expressed in many tissues. Not found in heart, liver, spleen and testis. Relatively highly expressed in fetal brain. Isoform LMX1A-4B is expressed in testis. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MEGIMNPYTALPTPQQLLAIEQSVY SSDPFRQGLTPPQMPGDHMHPYGAE PLFHDLDSDDTSLSNLGDCFLATSE AGPLQSRVGNPIDHLYSMQNSYFTS |
Sequence Similarities : | Contains 1 homeobox DNA-binding domain.Contains 2 LIM zinc-binding domains. |
Gene Name : | LMX1A LIM homeobox transcription factor 1, alpha [ Homo sapiens ] |
Official Symbol : | LMX1A |
Synonyms : | LMX1A; LIM homeobox transcription factor 1, alpha; LMX1; LIM homeobox transcription factor 1-alpha; LMX1.1; |
Gene ID : | 4009 |
mRNA Refseq : | NM_001174069 |
Protein Refseq : | NP_001167540 |
MIM : | 600298 |
Uniprot ID : | Q8TE12 |
Chromosome Location : | 1q24.1 |
Function : | metal ion binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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