"LOXL2" Related Products

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Recombinant Human LOXL2 protein, FLAG-tagged

Cat.No.: LOXL2-29651TH
Product Overview: Recombinant Human LOXL2(500–end) fused with FLAG tag at C-terminal was expressed in Insect cells.
Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Source: Insect cells
Species: Human
Tag: FLAG
Form: 40 mM Tris HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, and 20% glycerol.
Molecular Mass: 32 kDa
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage: >6 months at –80 centigrade. Avoid freeze/thaw cycles.
Concentration: 0.07mg/ml
Gene Name: LOXL2 lysyl oxidase-like 2 [ Homo sapiens ]
Official Symbol: LOXL2
Synonyms: LOXL2; lysyl oxidase-like 2; lysyl oxidase homolog 2; WS9 14; lysyl oxidase related 2; lysyl oxidase-like protein 2; lysyl oxidase-related protein 2; lysyl oxidase-related protein WS9-14; LOR2; WS9-14;
Gene ID: 4017
mRNA Refseq: NM_002318
Protein Refseq: NP_002309
MIM: 606663
UniProt ID: Q9Y4K0
Chromosome Location: 8p21.3
Function: copper ion binding; electron carrier activity; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; scavenger receptor activity;

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