Recombinant Human Interleukin 1 Receptor-Like 2

• Cat.No.: IL1RL2-1639H

Specification

• Cat. No.: IL1RL2-1639H
• Description: Interleukin-1 receptor related protein 2 (IL-1 Rrp2) is a receptor for IL-1F6 which is a proinflammatory member of IL-1 family. IL-1F8, and IL-1F9 also signal through IL-1Rrp2 and IL-1RAcP. IL-1F6, IL-1F8 and Il-1F9 are agonists and, along with their receptor IL-1Rrp2, are highly expressed in epithelial cells suggesting a role in immune defense in the skin and the gastrointestinal (GI) tract including the mouth. Synovial fibroblasts and articular chondrocytes also express IL-1Rrp2 and respond to IL-1F8, indicating a possible role in rheumatoid arthritis (RA).
• Source: Sf 21 Insect Cells.
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Molecular Weight: The predicted molecular weight of Recombinant Human IL-1 Rrp2 is Mr 62.8 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 80 kDa.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: IL1RL2 interleukin 1 receptor-like 2 [ Homo sapiens ]
• Synonyms:
  interleukin 1 receptor-like 2; IL1RRP2; IL1R-rp2; IL1RL2; interleukin-1 receptor-related protein 2; IL-1Rrp2; IL1R-rp2; IL1RRP2
• Gene ID: 8808
• mRNA Refseq: NM_003854
• Protein Refseq: NP_003845
• MIM: 604512
• UniProt ID: Q9HB29
• Chromosome Location: 2q12
• Function: interleukin-1, Type I, activating receptor activity; transmembrane receptor activity