Recombinant Human NEDD9, His-tagged

• Cat.No.: NEDD9-29304TH
• Product Overview: Recombinant fragment, corresponding to amino acids 414-834 of Human HEF1 with an N terminal His tag. Observed mwt: 52 kDa predicted mwt: 49 kDa

Specification

• Description: Enhancer of filamentation 1 is a protein that in humans is encoded by the NEDD9 gene.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Widely expressed. Higher levels detected in kidney, lung, and placenta. Also detected in T-cells, B-cells and diverse cell lines. The protein has been detected in lymphocytes, in diverse cell lines, and in lung tissues.
• Form: Lyophilised:Reconstitute with 116 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: QRLQQALEMGVSSLMALVTTDWRCYGYMERHINEIRTAVD KVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQR VEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRF VMVAKTVPDDAKQLTTTINTNAEALFRPGPGSLHLKNG PESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKALPPGL SKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKEL LEKENIMKQNKMQLEHHQLSQFQLLEQEITKPVENDIS KWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTL TRQVTAQDIRNKVMNSSNQLCEQLKTIVMATKMAALHY PSTTALQEMVHQVTDLSRNAQLFKRSLLEMATF
• Sequence Similarities: Belongs to the CAS family.Contains 1 SH3 domain.

Gene Information

• Gene Name: NEDD9 neural precursor cell expressed, developmentally down-regulated 9 [ Homo sapiens ]
• Official Symbol: NEDD9
• Synonyms: NEDD9; neural precursor cell expressed, developmentally down-regulated 9; enhancer of filamentation 1; Cas scaffolding protein family member 2; CAS L; Cas like; CASS2; HEF1
• Gene ID: 4739
• mRNA Refseq: NM_001142393
• Protein Refseq: NP_001135865
• MIM: 602265
• Uniprot ID: Q14511
• Chromosome Location: 6p25-p24
• Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem
• Function: protein binding