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Recombinant Human Plasminogen Activator, Urokinase Receptor

Cat. No. : PLAUR-412H
Description : Urokinase-type plasminogen activator receptor (uPAR) is a glycolipid-anchored three-domain membrane protein playing a central role in pericellular plasminogen activation. It is also involved in many physiological and pathological events that include cell migration and tissue invasion. uPAR may play a critical role in cancer invasion and metastasis.
Source : NSO cells.
Molecular Weight : The predicted molecular weight of Recombinant Human uPAR is 31 kDa. However, the actual molecular weight as observed by migration on SDS Page is 40-55 kDa.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : PLAUR plasminogen activator, urokinase receptor [ Homo sapiens ]
Synonyms : PLAUR; plasminogen activator, urokinase receptor; CD87; UPAR; URKR; Urokinase plasminogen activator surface receptor; uPAR; U-PAR; Monocyte activation antigen Mo3; MO3
Gene ID : 5329
mRNA Refseq : NM_001005376
Protein Refseq : NP_001005376
MIM : 173391
UniProt ID : Q03405
Chromosome Location : 19q13
Pathway : Complement and coagulation cascades; Hemostasis; Metabolism of proteins
Function : U-plasminogen activator receptor activity; enzyme binding

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