Recombinant Human Plasminogen Activator, Urokinase Receptor

• Cat.No.: PLAUR-412H

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Non
• Description: Urokinase-type plasminogen activator receptor (uPAR) is a glycolipid-anchored three-domain membrane protein playing a central role in pericellular plasminogen activation. It is also involved in many physiological and pathological events that include cell migration and tissue invasion. uPAR may play a critical role in cancer invasion and metastasis.
• Molecular Weight: The predicted molecular weight of Recombinant Human uPAR is 31 kDa. However, the actual molecular weight as observed by migration on SDS Page is 40-55 kDa.
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: PLAUR plasminogen activator, urokinase receptor [ Homo sapiens ]
• Synonyms: PLAUR; plasminogen activator, urokinase receptor; CD87; UPAR; URKR; Urokinase plasminogen activator surface receptor; uPAR; U-PAR; Monocyte activation antigen Mo3; MO3
• Gene ID: 5329
• mRNA Refseq: NM_001005376
• Protein Refseq: NP_001005376
• MIM: 173391
• UniProt ID: Q03405
• Chromosome Location: 19q13
• Pathway: Complement and coagulation cascades; Hemostasis; Metabolism of proteins
• Function: U-plasminogen activator receptor activity; enzyme binding