Recombinant Human NFYA
Cat.No. : | NFYA-30385TH |
Product Overview : | Recombinant fragment of Human NFYA Isoform short with N-terminal proprietary tag. Mol Wt 36.63 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | AIQRIPLPGAEMLEEEPLYVNAKQY NRILKRRQARAKLEAEGKIPKERRK YLHESRHRHAMARKRGEGGRFFSPK EKDSPHMQDPNQADEEAMTQIIRVS * |
Gene Name : | NFYA nuclear transcription factor Y, alpha [ Homo sapiens ] |
Official Symbol : | NFYA |
Synonyms : | NFYA; nuclear transcription factor Y, alpha; nuclear transcription factor Y subunit alpha; CBF B; HAP2; NF YA; |
Gene ID : | 4800 |
mRNA Refseq : | NM_002505 |
Protein Refseq : | NP_002496 |
MIM : | 189903 |
Uniprot ID : | P23511 |
Chromosome Location : | 6p21.3 |
Pathway : | Activation of Chaperones by ATF6-alpha, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Diabetes pathways, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; |
Function : | DNA binding; protein binding; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
NFYA-2838R | Recombinant Rhesus Macaque NFYA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFYA-3636R | Recombinant Rat NFYA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFYA-3619H | Recombinant Human NFYA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFYA-4699H | Recombinant Human NFYA Protein (Met1-Ser318) | +Inquiry |
NFYA-200H | Recombinant Human NFYA Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NFYA-3841HCL | Recombinant Human NFYA 293 Cell Lysate | +Inquiry |
NFYA-3840HCL | Recombinant Human NFYA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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