Recombinant Human PDE4C

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Recombinant Human PDE4C

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Cat.No. : PDE4C-30820TH
Product Overview : Recombinant full length Human PDE4C protein with N-terminal proprietary tag, expressed in a Baculovirus infected Sf9 cell expression system, 106 kDa.
Description : The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Biological activity : Specific Activity: 17230 pmol/min/μg.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Gene Name : PDE4C phosphodiesterase 4C, cAMP-specific [ Homo sapiens ]
Official Symbol : PDE4C
Synonyms : PDE4C; phosphodiesterase 4C, cAMP-specific; DPDE1, phosphodiesterase 4C, cAMP specific (dunce (Drosophila) homolog phosphodiesterase E1); cAMP-specific 3,5-cyclic phosphodiesterase 4C; phosphodiesterase E1 dunce homolog (Drosophila);
Gene ID : 5143
mRNA Refseq : NM_000923
Protein Refseq : NP_000914
MIM : 600128
Uniprot ID : Q08493
Chromosome Location : 19p13.11
Pathway : DARPP-32 events, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Opioid Signalling, organism-specific biosystem;
Function : 3,5-cyclic-AMP phosphodiesterase activity; drug binding; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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