|Product Overview :||Native Human PLAU was purified from Human urine.|
|Description :||Urokinase (UK) is a serine protease, which is one of biological plasminogen activators.
It is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. It can be obtained from human urine or kidney cell culture.
|Source :||Human urine|
|Form :||The Urokinase was lyophilized from a concentrated (1mg/ml) solution containing phosphate buffer.|
|Molecular Mass :||54,000 Dalton|
|Protein length :||411 amino acids|
|Purity :||Greater than 94.0% as determined by SDS-PAGE.|
|Notes :||Free of: Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.|
|Storage :||Lyophilized Urokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18 centigrade. Upon reconstitution Urokinase should be stored at 4 centigrade between 2-7 days and for future use below -18 centigrade.
Please prevent freeze-thaw cycles.
|Reconstitution :||It is recommended to reconstitute the lyophilized Urokinase in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.|
|Gene Name :||PLAU plasminogen activator, urokinase [ Homo sapiens ]|
|Official Symbol :||PLAU|
|Synonyms :||PLAU; plasminogen activator, urokinase; urokinase-type plasminogen activator; UPA; URK; U-plasminogen activator; plasminogen activator, urinary; ATF; QPD; u-PA; BDPLT5;|
|Gene ID :||5328|
|mRNA Refseq :||NM_001145031|
|Protein Refseq :||NP_001138503|
|UniProt ID :||P00749|
|Chromosome Location :||10q24|
|Pathway :||ATF-2 transcription factor network, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem|
|Function :||peptidase activity; protein binding; serine-type endopeptidase activity;|