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Native Human Urokinase protein

Cat.No.: PLAU-31689TH
Product Overview: Native Human PLAU was purified from Human urine.
Description: Urokinase (UK) is a serine protease, which is one of biological plasminogen activators.
It is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. It can be obtained from human urine or kidney cell culture.
Source: Human urine
Species: Human
Form: The Urokinase was lyophilized from a concentrated (1mg/ml) solution containing phosphate buffer.
Bio-activity: 174,827IU/mg
Molecular Mass: 54,000 Dalton
Protein length: 411 amino acids
Purity: Greater than 94.0% as determined by SDS-PAGE.
Notes: Free of: Hepatitis B surface antigen, Hepatitis C antibody and HIV I and II.
Storage: Lyophilized Urokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18 centigrade. Upon reconstitution Urokinase should be stored at 4 centigrade between 2-7 days and for future use below -18 centigrade.
Please prevent freeze-thaw cycles.
Reconstitution: It is recommended to reconstitute the lyophilized Urokinase in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Gene Name: PLAU plasminogen activator, urokinase [ Homo sapiens ]
Official Symbol: PLAU
Synonyms: PLAU; plasminogen activator, urokinase; urokinase-type plasminogen activator; UPA; URK; U-plasminogen activator; plasminogen activator, urinary; ATF; QPD; u-PA; BDPLT5;
Gene ID: 5328
mRNA Refseq: NM_001145031
Protein Refseq: NP_001138503
MIM: 191840
UniProt ID: P00749
Chromosome Location: 10q24
Pathway: ATF-2 transcription factor network, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem
Function: peptidase activity; protein binding; serine-type endopeptidase activity;

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