"PLK3" Related Products

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Recombinant Human PLK3, His-tagged

Cat.No.: PLK3-31032TH
Product Overview: Recombinant fragment, corresponding to amino acids 58-339 of Human PLK3, with N terminal His tag.
Description: Cytokine-inducible kinase is a putative serine/threonine kinase.CNK contains both a catalytic domain and a putative regulatory domain.It may play a role in regulation of cell cycle progression and tumorigenesis.
Conjugation: HIS
Tissue specificity: Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. May have a short half-live. In cells of hematopoietic origin, strongly and exclusively detected in
Biological activity: Activity: 500 U/mg. One unit is defined as the amount of enzyme that willphosphorylate 1 nmol of casein substrate per minute at pH 7.4 and 30C. Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3 uM Na-orthovanadate, 0.5 mM ATP.
Form: Liquid
Storage buffer: Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids: SGR TYLKGRLLGK GGFARCYEAT DTETGSAYAV KVIPQSRVAK PHQREKILNE IELHRDLQHRHIVRFSHHFE DADNIYIFLE LCSRKSLAHI WKARHTLLEP EVRYYLRQIL SGLKYLHQRGILHRDLKLGN FFITENMELK VGDFGLAARL EPPEQRKKTI CGTPNYVAPE VLLRQGHGPEADVWSLGCVM YTLLCGSPPF ETADLKETYR CIKQVHYTLP ASLSLPARQL LAAILRASPRDRPSIDQILR HDFFTKGYTP DRLPISSCVT VPDLTPPNP
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.Contains 2 POLO box domains.Contains 1 protein kinase domain.
Gene Name: PLK3 polo-like kinase 3 [ Homo sapiens ]
Official Symbol: PLK3
Synonyms: PLK3; polo-like kinase 3; CNK, cytokine inducible kinase , polo like kinase 3 (Drosophila); serine/threonine-protein kinase PLK3; FNK; PRK;
Gene ID: 1263
mRNA Refseq: NM_004073
Protein Refseq: NP_004064
MIM: 602913
Uniprot ID: Q9H4B4
Chromosome Location: 1p34.1
Pathway: Direct p53 effectors, organism-specific biosystem; PLK3 signaling events, organism-specific biosystem; Polo-like kinase signaling events in the cell cycle, organism-specific biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem;
Function: ATP binding; nucleotide binding; p53 binding; protein binding; protein serine/threonine kinase activity;

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