|Product Overview :
||Recombinant full length human His-tagged POLR2E isolated from an E. coli strain that carries the coding sequence of the protein under the control of a T7 promoter.
||This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.
||>95% by SDS-PAGE
|Storage buffer :
||Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequence Similarities :
||Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.