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Recombinant Human PRDX2

Cat.No.: PRDX2-30464TH
Product Overview: Recombinant full length Human Peroxiredoxin 2 , 22 kDa.
Description: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.
Source: E. coli
Biological activity: Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX2 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25 C for 1 minute.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN
Sequence Similarities: Belongs to the ahpC/TSA family.Contains 1 thioredoxin domain.
Gene Name: PRDX2 peroxiredoxin 2 [ Homo sapiens ]
Official Symbol: PRDX2
Synonyms: PRDX2; peroxiredoxin 2; TDPX1; peroxiredoxin-2; MGC4104; natural killer enhancing factor B; NKEFB; PRP; PRX2; PRXII; thiol specific antioxidant 1; thioredoxin peroxidase 1; thioredoxin dependent peroxide reductase 1; torin; TSA;
Gene ID: 7001
mRNA Refseq: NM_005809
Protein Refseq: NP_005800
MIM: 600538
Uniprot ID: P32119
Chromosome Location: 19p13.2
Pathway: Selenium Pathway, organism-specific biosystem;
Function: antioxidant activity; antioxidant activity; oxidoreductase activity; thioredoxin peroxidase activity; thioredoxin peroxidase activity;

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