Recombinant Human Dipeptidyl-Peptidase 8, GST-tagged

• Cat.No.: DPP8-516H
• Product Overview: Recombinant Human DPP8 (full length) was expressed in aBaculovirus infected Sf9 cellexpression system with N-terminal GST tag. MW=129.3 kDa.

Specification

• Cat. No.: DPP8-516H
• Description: Dipeptidyl peptidase 8 is an enzyme that in humans is encoded by the DPP8 gene. This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described.
• Source: Sf9.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Purity: > 70%.
• Stability: >6 months at -80°C.

Gene Information

• Gene Name: DPP8 dipeptidyl-peptidase 8 [ Homo sapiens ]
• Synonyms: dipeptidyl-peptidase 8; DP8; DPRP1; MSTP141; FLJ14920; FLJ20283; MGC26191; DPP8; dipeptidylpeptidase 8; prolyl dipeptidase DPP8; dipeptidyl peptidase VIII; dipeptidyl peptidase IV-related protein-1; DPRP-1; EC 3.4.14.5; Dipeptidyl peptidase IV-related protein 1; Dipeptidyl peptidase VIII; Prolyl dipeptidase DPP8
• Gene ID: 54878
• mRNA Refseq: NM_017743
• Protein Refseq: NP_060213
• MIM: 606819
• UniProt ID: Q6V1X1
• Chromosome Location: 15q22
• Function: aminopeptidase activity; serine-type peptidase activity; peptidase activity; dipeptidyl-peptidase activity