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Recombinant Human PRDX5

Cat.No.: PRDX5-30762TH
Product Overview: Recombinant full length Human Peroxiredoxin 5; amino acids 53-214, 17kDa.
Description: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.
Source: E. coli
Tissue specificity: Widely expressed.
Biological activity: Specific activity : 2.12 U/mgOne unit will cause the oxidation of 1μmole of NADPH at 25°C at pH 7.5.
Form: Lyophilised:Packaging size : 0.5 mg
Storage buffer: Preservative: NoneConstituents: 20mM HEPES, pH 7.4
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the peroxiredoxin 2 family.Contains 1 thioredoxin domain.
Gene Name: PRDX5 peroxiredoxin 5 [ Homo sapiens ]
Official Symbol: PRDX5
Synonyms: PRDX5; peroxiredoxin 5; peroxiredoxin-5, mitochondrial; ACR1; Alu co repressor 1; antioxidant enzyme B166; AOEB166; B166; liver tissue 2D page spot 71B; MGC117264; MGC142283; MGC142285; peroxisomal antioxidant enzyme; PLP; PMP20; PRDX6; PRXV; SBBI10; thio
Gene ID: 25824
mRNA Refseq: NM_012094
Protein Refseq: NP_036226
MIM: 606583
Uniprot ID: P30044
Chromosome Location: 11q13
Pathway: Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; Selenium Pathway, organism-specific biosystem;
Function: cysteine-type endopeptidase inhibitor activity involved in apoptotic process; oxidoreductase activity; peroxidase activity; peroxiredoxin activity;

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