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Native Human PROS1

Cat.No. : PROS1-31218TH
Product Overview : Purified full length native human Protein S, isolated from fresh frozen plasma, is a single chain protein containing 10 gla residues in the NH2-terminal domain and 4 epidermal growth factor (EGF) domains, MW 69kDa.Post translational modifications: one bet
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Description : This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.
Tissue specificity : Plasma.
Form : Liquid
Purity : Immunogen affinity purified
Storage buffer : Preservative: NoneConstituents: 50% Glycerol
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities : Contains 4 EGF-like domains.Contains 1 Gla (gamma-carboxy-glutamate) domain.Contains 2 laminin G-like domains.
Gene Name : PROS1 protein S (alpha) [ Homo sapiens ]
Official Symbol : PROS1
Synonyms : PROS1; protein S (alpha); PROS; vitamin K-dependent protein S;
Gene ID : 5627
mRNA Refseq : NM_000313
Protein Refseq : NP_000304
MIM : 176880
Uniprot ID : P07225
Chromosome Location : 3p11-q11.2
Pathway : Cell surface interactions at the vascular wall, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem;
Function : calcium ion binding; endopeptidase inhibitor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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