Recombinant Human PSMB10, His-tagged
Cat.No. : | PSMB10-31221TH |
Product Overview : | Recombinant full length protein, (amino acids 40-237, excluding propeptide) of Human PSMB10 with N terminal His tag; 255 amino acids, 26.9 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. |
Protein length : | 198 amino acids |
Conjugation : | HIS |
Molecular Weight : | 26.900kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.02% Tris HCl, 40% Glycerol, 0.58% Sodium chloride |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMTTIA GLVFQDGVILGADTRATNDSVVADK SCEKIHFIAPKIYCCGAGVAADAEM TTRMVASKMELHALSTGREPRVATV TRILRQTLFRYQGHVGASLIVGGVD LTGPQLYGVHPHGSYSRLPFTALGS GQDAALAVLEDRFQPNMTLEAAQGL LVEAVTAGILGDLGSGGNVDACVIT KTGAKLLRTLSSPTEPVKRSGRYHF VPGTTAVLTQTVKPLTLELVEETVQ AMEVE |
Sequence Similarities : | Belongs to the peptidase T1B family. |
Gene Name : | PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 [ Homo sapiens ] |
Official Symbol : | PSMB10 |
Synonyms : | PSMB10; proteasome (prosome, macropain) subunit, beta type, 10; MECL1; proteasome subunit beta type-10; beta2i; LMP10; MGC1665; |
Gene ID : | 5699 |
mRNA Refseq : | NM_002801 |
Protein Refseq : | NP_002792 |
MIM : | 176847 |
Uniprot ID : | P40306 |
Chromosome Location : | 16q22.1 |
Pathway : | APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; |
Function : | peptidase activity; threonine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
PSMB10-3472R | Recombinant Rhesus Macaque PSMB10 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMB10-7210M | Recombinant Mouse PSMB10 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMB10-4429R | Recombinant Rat PSMB10 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMB10-3654R | Recombinant Rhesus monkey PSMB10 Protein, His-tagged | +Inquiry |
PSMB10-6864H | Recombinant Human Proteasome (prosome, macropain) Subunit, Beta Type, 10, His-tagged | +Inquiry |
◆ Lysates | ||
PSMB10-512HCL | Recombinant Human PSMB10 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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