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Recombinant Human RBM14, His-tagged

Cat.No. : RBM14-31045TH
Product Overview : Recombinant full length protein, corresponding to amino acids 1-669 of Human RBM14 with N terminal His tag, 93kDa.
  • Specification
  • Gene Information
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Description : This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 159 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFV HMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNT WKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAF VHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPG LAVQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNS TGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTA QPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAAS YRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQP SASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSY GAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQS AASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYS SQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQ PVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAY GAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRG QPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTR LSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSES QLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRA AQMHSGYQRRM
Gene Name : RBM14 RNA binding motif protein 14 [ Homo sapiens ]
Official Symbol : RBM14
Synonyms : RBM14; RNA binding motif protein 14; RNA-binding protein 14; COAA; coactivator activator; DKFZp779J0927; SIP; SYT interacting protein; SYTIP1;
Gene ID : 10432
mRNA Refseq : NM_001198836
Protein Refseq : NP_001185765
MIM : 612409
Uniprot ID : Q96PK6
Chromosome Location : 11q13.2
Function : RNA binding; RNA polymerase II transcription cofactor activity; ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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