Recombinant Human RPIA, His-tagged

• Cat.No.: RPIA-31147TH
• Product Overview: Recombinant fragment, corresponding to amino acids 32-311 of Human RPIA with N terminal His tag; Predicted MWt 31 kDa.

Specification

• Description: The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 64 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: NSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPA PSTMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIV HAVQRIAERVKQENLNLVCIPTSFQARQLILQYGLTLS DLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIV AGYASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPV SRAVSQKFGGVVELRMAVNKAGPVVTDNGNFILDWKFD RVHKWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQDG SVNMREKPFC
• Sequence Similarities: Belongs to the ribose 5-phosphate isomerase family.

Gene Information

• Gene Name: RPIA ribose 5-phosphate isomerase A [ Homo sapiens ]
• Official Symbol: RPIA
• Synonyms: RPIA; ribose 5-phosphate isomerase A; ribose-5-phosphate isomerase; ribose 5 phosphate epimerase
• Gene ID: 22934
• mRNA Refseq: NM_144563
• Protein Refseq: NP_653164
• MIM: 180430
• Uniprot ID: P49247
• Chromosome Location: 2p11.2
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; Pentose Phosphate Pathway, organism-specific biosystem; Pentose phosphate pathway, organism-specific biosystem; Pentose phosphate pathway, conserved biosystem
• Function: isomerase activity; monosaccharide binding; ribose-5-phosphate isomerase activity