"Il1r2" Related Products

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Recombinant Mouse Interleukin 1 Receptor, Type II

Cat. No. : Il1r2-1754M
Description : Interleukin 1 receptor type II (IL1R2), also known as CD121b (Cluster of Differentiation 121b), is a transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. It is a decoy receptor known for its ability to buffer IL-1 effects. IL-1RII is involved in the control of the proinflammatory state that takes place in the endometrium during the premenstrual and menstrual periods. IL-1RII can neutralize IL-1 beta and counteract its effect on endometrial stromal cells, and may provide a new clinical strategy for the treatment of endometriosis.
Molecular Weight : The predicted molecular weight of Recombinant Mouse IL-1 RII is Mr 64.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa.
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : Il1r2 interleukin 1 receptor, type II [ Mus musculus ]
Synonyms : Il1r2; interleukin 1 receptor, type II; CD121b; Il1r-2; IL-1 receptor beta chain
Gene ID : 16178
mRNA Refseq : NM_010555
Protein Refseq : NP_034685
UniProt ID : P27931
Chromosome Location : 1 B; 1 19.5 cM
Pathway : Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; MAPK signaling pathway
Function : interleukin-1 receptor activity; interleukin-1, Type II, blocking receptor activity; receptor activity

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