"SIGIRR" Related Products

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Recombinant Human SIGIRR, Fc-tagged

Cat.No.: SIGIRR-28784TH
Product Overview: Recombinant fragment corresponding to amino acids 1-118 of Human SIGIRR fused at the C-terminus to the Fc portion of Human IgG1; MWt 50 kDa .
Description: Single Ig IL-1-related receptor is a protein that in humans is encoded by the SIGIRR gene.
Protein length: 118 amino acids
Conjugation: Fc
Molecular Weight: 50.000kDa inclusive of tags
Source: HEK 293 cells
Tissue specificity: Mainly expressed in epithelial tissues such as kidney, lung and gut.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: PBS
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the interleukin-1 receptor family.Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 TIR domain.
Gene Name: SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain [ Homo sapiens ]
Official Symbol: SIGIRR
Synonyms: SIGIRR; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single Ig IL-1-related receptor; single immunoglobulin domain IL1R1 related; TIR8;
Gene ID: 59307
mRNA Refseq: NM_001135053
Protein Refseq: NP_001128525
MIM: 605478
Uniprot ID: Q6IA17
Chromosome Location: 11p15.5
Pathway: Activated TLR4 signalling, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88:Mal cascade initiated on plasma membrane, organism-specific biosystem; Toll Like Receptor 2 (TLR2) Cascade, organism-specific biosystem;
Function: protein binding; transmembrane signaling receptor activity;

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