Recombinant Human SNX1, T7 -tagged SNX1-30610TH

Cat.No.:	SNX1-30610TH
Product Overview:	Recombinant full length human SNX1 with N-terminal T7 tag.
Description:	This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Conjugation:	T7
Source:	E. coli
Form:	Liquid
Purity:	>95% by SDS-PAGE
Storage buffer:	Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8
Storage:	Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities:	Belongs to the sorting nexin family.Contains 1 BAR domain.Contains 1 PX (phox homology) domain.

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Gene Name:	SNX1 sorting nexin 1 [ Homo sapiens ]
Official Symbol:	SNX1
Synonyms:	SNX1; sorting nexin 1; sorting nexin-1; HsT17379; MGC8664; SNX1A; Vps5;
Gene ID:	6642
mRNA Refseq:	NM_001242933
Protein Refseq:	NP_001229862
MIM:	601272
Uniprot ID:	Q13596
Chromosome Location:	15q22.31
Pathway:	TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
Function:	lipid binding; phosphatidylinositol binding; protein binding; protein transporter activity;