Recombinant Human SNX1, T7 -tagged

• Cat.No.: SNX1-30610TH
• Product Overview: Recombinant full length human SNX1 with N-terminal T7 tag.

Specification

• Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
• Conjugation: T7
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the sorting nexin family.Contains 1 BAR domain.Contains 1 PX (phox homology) domain.

Gene Information

• Gene Name: SNX1 sorting nexin 1 [ Homo sapiens ]
• Official Symbol: SNX1
• Synonyms: SNX1; sorting nexin 1; sorting nexin-1; HsT17379; MGC8664; SNX1A; Vps5
• Gene ID: 6642
• mRNA Refseq: NM_001242933
• Protein Refseq: NP_001229862
• MIM: 601272
• Uniprot ID: Q13596
• Chromosome Location: 15q22.31
• Pathway: TGF-beta Receptor Signaling Pathway, organism-specific biosystem
• Function: lipid binding; phosphatidylinositol binding; protein binding; protein transporter activity