Recombinant Human SNX4, His-tagged

• Cat.No.: SNX4-31429TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 1-450 of Human SNX4 with an N terminal His tag; Predicted MWt 53 kDa.

Specification

• Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 128 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGE ESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQE TYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSY LLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERR RIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET GFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQS VISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEK EMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYL FYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELV TGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGE QQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALIS YAVMQISMCKKGIQVWTNAKECFSKM
• Sequence Similarities: Belongs to the sorting nexin family.Contains 1 PX (phox homology) domain.

Gene Information

• Gene Name: SNX4 sorting nexin 4 [ Homo sapiens ]
• Official Symbol: SNX4
• Synonyms: SNX4; sorting nexin 4; sorting nexin-4; ATG24B
• Gene ID: 8723
• mRNA Refseq: NM_003794
• Protein Refseq: NP_003785
• MIM: 605931
• Uniprot ID: O95219
• Chromosome Location: 3q21.2
• Pathway: TGF-beta Receptor Signaling Pathway, organism-specific biosystem
• Function: lipid binding; phosphatidylinositol binding; protein binding