Recombinant Human Poly (ADP-ribose) Polymerase 2, GST-tagged

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Recombinant Human Poly (ADP-ribose) Polymerase 2, GST-tagged

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Cat. No. : PARP2-433H
Product Overview : Recombinant Human PARP2, amino-acids 2-583 with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW = 92kDa.
Description : Poly (ADP-ribose) polymerase (PARP) is a protein involved in a number of cellular processes involving mainly DNA repair and programmed cell death.
Source : Sf9 cell.
Purity : >80%.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
Stability : >6 months at –80°C.
PDB rendering based on 1gs0. :

Gene Name : PARP2 poly (ADP-ribose) polymerase 2 [ Homo sapiens ]
Synonyms : PARP2; poly (ADP-ribose) polymerase 2; ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; poly(ADP-ribose) synthetase; EC 2.4.2.30; ADPRT2; PARP-2; ADPRTL2; ADPRTL3; pADPRT-2
Gene ID : 10038
mRNA Refseq : NM_001042618
Protein Refseq : NP_001036083
MIM : 607725
UniProt ID : Q9UGN5
Chromosome Location : 14q11.2-q12
Pathway : Base excision repair
Function : DNA binding; NAD or NADH binding; NAD+ ADP-ribosyltransferase activity; identical protein binding; protein N-terminus binding; transcription factor binding; transferase activity, transferring glycosyl groups; zinc ion binding

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