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| Cat. No.: | PDE10A-440H |
| Product Overview: | Recombinant Human PDE10A, full length with N-terminal GST tag expressed in aBaculovirus infected Sf9 cellexpression system. MW = 116kDa. |
| Description: | Phosphodiesterase 10A is an enzyme that in humans is encoded by the PDE10A gene. |
| Source: | Sf9 cell. |
| Purity: | >60%. |
| Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Formulated In: | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT. |
| Stability: | >6 months at –80°C. |
| Gene Name: | PDE10A phosphodiesterase 10A [ Homo sapiens ] |
| Synonyms: | PDE10A; phosphodiesterase 10A; FLJ11894; FLJ25677; HSPDE10A; OTTHUMP00000017586; phosphodiesterase 10A1 (PDE10A1); dJ416F21.1 (phosphodiesterase 10A); EC 3.1.4.17; EC 3.1.4.35 |
| Gene ID: | 10846 |
| mRNA Refseq: | NM_001130690 |
| Protein Refseq: | NP_001124162 |
| MIM: | 610652 |
| UniProt ID: | Q9Y233 |
| Chromosome Location: | 6q26 |
| Pathway: | Progesterone-mediated oocyte maturation; Purine metabolism; Signaling by GPCR |
| Function: | 3",5"-cyclic-GMP phosphodiesterase activity; cAMP binding; cGMP binding; hydrolase activity; magnesium ion binding; nucleotide binding; zinc ion binding |
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