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Recombinant Human STUB1

Cat.No.: STUB1-30458TH
Product Overview: Recombinant human STUB1 fragment, C-terminal.
Description: STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al.
Source: E. coli
Tissue specificity: Highly expressed in skeletal muscle, heart, pancreas, brain and placenta. Detected in kidney, liver and lung.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 50mM HEPES/KOH, 50mM Potassium chloride, 5mM DTT, pH 7.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Contains 3 TPR repeats.Contains 1 U-box domain.
Gene Name: STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase [ Homo sapiens ]
Official Symbol: STUB1
Synonyms: STUB1; STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase; STIP1 homology and U box containing protein 1; E3 ubiquitin-protein ligase CHIP; CHIP; HSPABP2; NY CO 7; SDCCAG7; UBOX1;
Gene ID: 10273
mRNA Refseq: NM_005861
Protein Refseq: NP_005852
MIM: 607207
Uniprot ID: Q9UNE7
Chromosome Location: 16p13.3
Pathway: Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem;
Function: Hsp70 protein binding; Hsp90 protein binding; SMAD binding; TPR domain binding; enzyme binding;

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