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Recombinant Human Protein Arginine Methyltransferase 6

Cat. No.: PRMT6-453H
Product Overview: Recombinant Human PRMT6, amino-acids 2-375(end), with N-terminal His-tag, MW=43 kDa, expressed in E. coli.
Description: Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.
Source: E.coli
Purity: >45%.
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, 20% glycerol, and 3 mM DTT.
Stability: >6 months at –80°C.
Gene Name: PRMT6 protein arginine methyltransferase 6 [ Homo sapiens ]
Synonyms: PRMT6; protein arginine methyltransferase 6; HRMT1L6; FLJ10559; FLJ51477;EC 2.1.1.125; protein arginine N-methyltransferase 6; Histone-arginine methyltransferase PRMT6;EC2.1.1.-; Protein arginine N-methyltransferase 6; HMT1 hnRNP methyltransferase-like 6 (S. cerevisiae); Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6
Gene ID: 55170
mRNA Refseq: NM_018137
Protein Refseq: NP_060607
MIM: 608274
UniProt ID: Q96LA8
Chromosome Location: 1p13.2
Function: histone binding; transferase activity; protein methyltransferase activity; histone methyltransferase activity (H2A-R3 specific); histone methyltransferase activity (H3-R2 specific); histone methyltransferase activity (H4-R3 specific); protein methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity

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