Recombinant Human TFF1
Cat.No. : | TFF1-27976TH |
Product Overview : | Recombinant Human Estrogen Inducible Protein pS2 |
- Specification
- Gene Information
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Description : | Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. |
Source : | E. coli |
Tissue specificity : | Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal g |
Form : | Lyophilised:Lyophilized without additives. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. |
Purity : | >95% by SDS-PAGE |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Contains 1 P-type (trefoil) domain. |
Gene Name : | TFF1 trefoil factor 1 [ Homo sapiens ] |
Official Symbol : | TFF1 |
Synonyms : | TFF1; trefoil factor 1; BCEI, breast cancer, estrogen inducible sequence expressed in; D21S21; HP1.A; HPS2; pNR 2; pS2; |
Gene ID : | 7031 |
mRNA Refseq : | NM_003225 |
Protein Refseq : | NP_003216 |
MIM : | 113710 |
Uniprot ID : | P04155 |
Chromosome Location : | 21q22.3 |
Pathway : | FOXA1 transcription factor network, organism-specific biosystem; |
Function : | growth factor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
TFF1-1537H | Recombinant Human TFF1 Protein (25-84 aa), His-tagged | +Inquiry |
TFF1-5687R | Recombinant Rat TFF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TFF1-050T | Active Recombinant Human TFF1 Protein | +Inquiry |
TFF1-1142H | Recombinant Human TFF1 Protein (Met1-Phe84), His-tagged | +Inquiry |
Tff1-6379M | Recombinant Mouse Tff1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
TFF1-1127HCL | Recombinant Human TFF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, FGFR3-targeted therapies are being developed for cancer treatment, particularly for patients with FGFR3 mutations.
FGFR3 testing can aid in diagnosing specific types of cancer, especially bladder cancer, where FGFR3 mutations are prevalent.
FGFR3-targeted therapies may involve small molecule inhibitors or monoclonal antibodies that specifically block the activity of mutated FGFR3.
Mutations in the FGFR3 gene can lead to the development of certain cancers, including bladder cancer and multiple myeloma.
FGFR3 testing is becoming more common, especially in cases where specific cancers associated with FGFR3 mutations are suspected.
Customer Reviews (3)
Write a reviewTFF1 protein is highly recommended for scientific research applications, especially in ELISA assays and protein electron microscopy structure analysis.
Its versatility in various biological applications, coupled with its compatibility with diverse techniques, makes it a preferred reagent for researchers in the field.
Scientists who have employed TFF1 protein in their experiments have praised its outstanding performance and reliability.
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