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Native Human THBS1

Cat.No.: THBS1-31515TH
Product Overview: Full length native mature Thrombospondin protein purified from Human platelets.
Description: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
Form: Lyophilised:Reconstitute with 250ul distilled water.
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Sucrose, 600mM Sodium chloride, 20mM Tris, 1mM Calcium chloride, pH 7.8
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the thrombospondin family.Contains 3 EGF-like domains.Contains 1 TSP C-terminal (TSPC) domain.Contains 1 TSP N-terminal (TSPN) domain.Contains 3 TSP type-1 domains.Contains 8 TSP type-3 repeats.Contains 1 VWFC domain.
Gene Name: THBS1 thrombospondin 1 [ Homo sapiens ]
Official Symbol: THBS1
Synonyms: THBS1; thrombospondin 1; thrombospondin-1; THBS; THBS 1; thrombospondin 1p180; TSP; TSP 1; TSP1;
Gene ID: 7057
mRNA Refseq: NM_003246
Protein Refseq: NP_003237
MIM: 188060
Uniprot ID: P07996
Chromosome Location: 15q15
Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem;
Function: calcium ion binding; collagen V binding; eukaryotic cell surface binding; fibrinogen binding; fibroblast growth factor 2 binding;

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