Recombinant Human THOP1, His-tagged

• Cat.No.: THOP1-29998TH
• Product Overview: Recombinant fragment, corresponding to amino acids 266-689 of Human Thimet Oligopeptidase with N terminal His tag; 424 amino acids, 55kDa.

Specification

• Description: Thimet oligopeptidase is an enzyme that in humans is encoded by the THOP1 gene.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 88 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: KSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPL GEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQ VEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAF HHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGK YGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADA PSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVE RDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLE KLIESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEE YARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYL WSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGS EDASAMLRRFLGRDPKQDAFLLSKGLQVGGCEPEPQVC
• Sequence Similarities: Belongs to the peptidase M3 family.

Gene Information

• Gene Name: THOP1 thimet oligopeptidase 1 [ Homo sapiens ]
• Official Symbol: THOP1
• Synonyms: THOP1; thimet oligopeptidase 1; thimet oligopeptidase
• Gene ID: 7064
• mRNA Refseq: NM_003249
• Protein Refseq: NP_003240
• MIM: 601117
• Uniprot ID: P52888
• Chromosome Location: 19p13.3
• Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem
• Function: metal ion binding; metalloendopeptidase activity; peptidase activity; peptide binding