"TNFRSF12A" Related Products


Recombinant Human TNFRSF12A, Fc-tagged

Cat.No.: TNFRSF12A-30127TH
Product Overview: Recombinant fragment: EQAPGTAPCSRGSSWSADL D KCMDCASC RA RPHSDFC LGC AAAPPA PFRL LWP , corresponding to amino acids 28-80 of Human TWEAKR
Description: Tumor necrosis factor receptor superfamily member 12A is a protein that in humans is encoded by the TNFRSF12A gene.
Conjugation: Fc
Source: E. coli
Tissue specificity: Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Biological activity: Biological Activity : Determined by its ability to inhibit TWEAK-induced weak cell death of HT29 cells. The expected ED50 for this effect is 1.0-3.0 μg/ml.
Form: Lyophilised:Reconstitute to 1mg/ml in sterile water.
Storage: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
Sequence Similarities: Contains 1 TNFR-Cys repeat.
Gene Name: TNFRSF12A tumor necrosis factor receptor superfamily, member 12A [ Homo sapiens ]
Official Symbol: TNFRSF12A
Synonyms: TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; tumor necrosis factor receptor superfamily member 12A; CD266; FN14; TweakR;
Gene ID: 51330
mRNA Refseq: NM_016639
Protein Refseq: NP_057723
MIM: 605914
Uniprot ID: Q9NP84
Chromosome Location: 16p13.3
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function: protein binding; receptor activity;

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